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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
22.42
Human Site:
S533
Identified Species:
35.24
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
S533
P
P
L
P
P
V
Y
S
M
E
T
E
T
P
T
Chimpanzee
Pan troglodytes
XP_518483
668
77639
S599
P
P
L
P
P
V
Y
S
M
E
T
E
T
P
T
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
T485
V
Y
S
M
E
T
E
T
P
T
A
E
D
I
Q
Dog
Lupus familis
XP_538927
602
69962
S533
P
P
L
P
P
V
Y
S
M
E
T
E
T
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
D461
I
P
V
A
M
E
T
D
G
P
Q
F
E
D
V
Rat
Rattus norvegicus
XP_001062510
563
65413
S494
P
P
L
P
P
V
Y
S
M
E
T
E
T
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
P391
Y
S
M
E
T
E
T
P
T
A
E
D
I
Q
L
Chicken
Gallus gallus
XP_419321
459
53699
I396
Y
Y
W
N
N
E
Y
I
M
S
L
I
S
D
N
Frog
Xenopus laevis
NP_001087638
506
58853
I443
N
K
T
I
H
G
L
I
Y
N
A
L
K
L
F
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
S532
E
G
G
M
P
I
Y
S
M
E
T
E
T
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
S623
R
A
L
C
D
Q
Y
S
E
N
S
D
S
A
Y
Honey Bee
Apis mellifera
XP_392477
724
84384
T511
I
K
G
I
T
N
T
T
I
G
T
I
S
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
S508
G
R
N
S
E
A
G
S
I
N
S
P
D
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
Q447
P
A
L
E
R
N
A
Q
K
H
W
N
Q
A
V
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
S689
N
C
N
A
L
Y
L
S
S
V
K
E
T
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
6.6
100
N.A.
6.6
100
N.A.
0
13.3
0
66.6
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
13.3
100
N.A.
13.3
20
0
73.3
N.A.
40
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
14
0
7
7
0
0
7
14
0
0
14
0
% A
% Cys:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
7
0
0
0
14
14
14
0
% D
% Glu:
7
0
0
14
14
20
7
0
7
34
7
47
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% F
% Gly:
7
7
14
0
0
7
7
0
7
7
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
14
0
0
14
0
7
0
14
14
0
0
14
7
7
0
% I
% Lys:
0
14
0
0
0
0
0
0
7
0
7
0
7
0
0
% K
% Leu:
0
0
40
0
7
0
14
0
0
0
7
7
0
7
7
% L
% Met:
0
0
7
14
7
0
0
0
40
0
0
0
0
7
0
% M
% Asn:
14
0
14
7
7
14
0
0
0
20
0
7
0
0
7
% N
% Pro:
34
34
0
27
34
0
0
7
7
7
0
7
0
34
0
% P
% Gln:
0
0
0
0
0
7
0
7
0
0
7
0
7
20
20
% Q
% Arg:
7
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
7
7
0
0
0
54
7
7
14
0
20
0
0
% S
% Thr:
0
0
7
0
14
7
20
14
7
7
40
0
40
0
34
% T
% Val:
7
0
7
0
0
27
0
0
0
7
0
0
0
0
14
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
14
14
0
0
0
7
47
0
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _